Serum levels of leptin and adiponectin in patients with multiple sclerosis

Abstract Background The role of adipokines such as leptin and adiponectin in regulating the immunity has been documented, however data concerning their consequence on multiple sclerosis (MS) Egyptian patients are deficient. aim this study is to demonstrate serum levels MS assess association with disease disability severity. A case–control including 60 subjects (30 30 age, sex body mass index-matched healthy controls) was performed. Results Serum level significantly higher among than controls ( P < 0.001) while not elevated = 0.24). There a significant positive correlation between (Expanded Disability Status Scale) r 0.678; 0.001), severity (Multiple Sclerosis Severity Score) 0.631; progression (progression index) 0.461; 0.01). no statistically disability, or progression. Conclusions had insignificant compared controls. Leptin potential However, useful biomarker disease,